Prozac in Drinking Water / Prozac in Streams Hurt Frogs fish / Newborns suffer WithdrawalTue, 10 Aug 2004An article in the UK Observer–”Stay calm everyone, there’s Prozac in the drinking water” (below) — reports that British environmentalists are calling for an “urgent investigation into the revelations, describing the build-up of the antidepressant [Prozac] as ‘hidden mass medication’.The article was forwarded to me by at least 12 concerned, knowledgeable people from the UK and US–their concern is justified. The UK Environment Agency has found that Prozac is building up both in river systems and groundwater used for drinking supplies. This is a direct result of the inordinately high quantity of antidepressants consumed and excreted into the environment.In 2002, the U.S. Geological Survey tested 139 rivers in 30 states and found that 80 percent of streams sampled by showed evidence of drugs, hormones, steroids and personal care products such as soaps and perfumes.In October, 2003, US scientists reported that Prozac and other pharmaceuticals were polluting US streams and affecting the development of fish and other wild life. According to the National Center for Health Statistics at the CDC, more than 61 million prescriptions for anti-depressants were prescribed by U.S. doctors in 2001. As pointed out, because prescriptions like anti-depressants are for chronic conditions, patients often take them for months and years at a time, making them more likely to build up in wastewaterCNN reported: “Researchers are working on several fronts to determine how big the problem is and just what short- and long-term ecological effects there might be on wildlife. Bryan Brooks, a toxicologist at Baylor University in Texas, discovered evidence of Prozac, an anti-depressant, in the brains, livers, and muscles of bluegill, caught downstream from the Pecan Creek Water Reclamation Plant in Denton, Texas, near Dallas”Marsha Black, an aquatic toxicologist at the University of Georgia found that low levels of common anti-depressants, including Prozac, Zoloft, Paxil and Celexa, cause development problems in fish, and metamorphosis delays in frogs.Frogs, fish and pharmaceuticals a troubling brew: >>more<<
Fish on Prozac: Anxious, anti-social, aggressive
When fish swim in waters tainted with antidepressant drugs, they become anxious, anti-social and sometimes even homicidal. New research has found that the pharmaceuticals, which are frequently showing up in U.S. streams, can alter genes responsible for building fish brains and controlling their behavior. Antidepressants are the most commonly prescribed medications in the United States; about 250 million prescriptions are filled every year. And they also are the highest-documented drugs contaminating waterways, which has experts worried about fish. “At high doses we expect brain changes,” said scientist Rebecca Klaper. “But we saw the gene expression changes and then behavioral changes at doses that we consider environmentally relevant.” Male minnows exposed to a small dose of Prozac in laboratories ignored females and took more time capturing prey. When the dose was increased, but still at levels found in some wastewater, males became aggressive, killing females in some cases.
Pharmaceutical Waste: Why Is It An Issue Now?
When fish swim in waters tainted with antidepressant drugs, they become anxious, anti-social and sometimes even homicidal.
New research has found that the pharmaceuticals, which are frequently showing up in U.S. streams, can alter genes responsible for building fish brains and controlling their behavior.
Antidepressants are the most commonly prescribed medications in the United States; about 250 million prescriptions are filled every year. And they also are the highest-documented drugs contaminating waterways, which has experts worried about fish. Traces of the drugs typically get into streams when people excrete them, then sewage treatment plants discharge the effluent.
Exposure to fluoxetine, known by the trade name Prozac, had a bizarre effect on male fathead minnows, according to new, unpublished researchby scientists at the University of Wisconsin-Milwaukee.
Male minnows exposed to a small dose of the drug in laboratories ignored females. They spent more time under a tile, so their reproduction decreased and they took more time capturing prey, according to Rebecca Klaper, a professor of freshwater sciences who spoke about her findings at a Society of Environmental Toxicology and Chemistry conference last fall. Klaper said the doses of Prozac added to the fishes’ water were “very low concentrations,” 1 part per billion, which is found in some wastewater discharged into streams.
When the dose was increased, but still at levels found in some wastewater, females produced fewer eggs and males became aggressive, killing females in some cases, Klaper said at the conference.
The drugs seem to cause these behavioral problems by scrambling how genes in the fish brains are expressed, or turned on and off. The minnows were exposed when they were a couple of months old and still developing. >>MORE<<
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