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Test anthrax vaccine on children: A bad biodefense policy idea 2011, Panel debates bioterrorism protection for children 2012.


Biosecurity,WMD — by Alan Wolfe on October 31, 2011
I was surprised, last week, to see this story in the Washington Post about the efforts of a working group of the National Biodefense Science Board. Seems that, back in April, the board decided to examine whether children should receive the standard anthrax vaccine in the event of a wide-area anthrax attack on the nation. Although it’s not explained well in the story, it is assumed that this would be a post-treatment administered under emergency matters after an attack, rather than as a pre-treatment.
“At the end of the day, do we want to wait for an attack and give it to millions and millions of children and collect data at that time?” saidDaniel B. Fagbuyi of Children’s National Medical Center in Washington, who chaired the group. “Or do we want to say: ‘How do we best protect our children?’ We can take care of Grandma and Grandpa, Uncle and Auntie. But right now, we have nothing for the children.”
Yes, oh who will think of the children? As the article explains, the vaccine has been tested for safety for the military, but it doesn’t explain that the vaccine’s efficacy is sometimes in question. Critics of the vaccine note that it hasn’t been tested against humans who have been exposed to a weaponized form of anthrax. And that’s true. There have been animal models that show the airborne vaccine should be both safe and efficacious for humans. And all of our researchers and veterinarians who work with anthrax use the vaccine, without any losses. Both the airborne vaccine and the natural form of vaccine work in the same way on the human body. So we’re pretty sure it’s a very good vaccine.
But back to the children. Medical experts and emergency responders have always been concerned about the “sensitive population” and how they are treated in the event of an emergency. Yes, it’s possible that an anthrax vaccine developed for adults might be too powerful for children or have detrimental side effects. We don’t know. But the chance of a wide-area anthrax attack affecting thousands, let alone “millions and millions of children,” is almost zero. Close enough to zero to not worry about it.
Except for this National Biodefense Science Board.  They decided, on a vote of 12-1, that in fact, we do need to have the vaccine tested on children in order to prepare for that day that is “not a matter of if, but when.”
“We need to know more about the safety and immunogenicity of the vaccine as we develop plans to use the vaccine on a large number of children in the event of a bioterrorist’s attack,” said Ruth L. Berkelman of Emory University, a panel member.
Now these are smart people. I don’t doubt their sincerity or intelligence. I do question their common sense and rationality. The absolute possibility of a transnational terrorist attack involving kilograms of anthrax to cause such an event are just insignificant compared to the storm of controversy and outcry if the US government starts testing the anthrax vaccine on kids.
It doesn’t matter if the side effects of the anthrax vaccine are far less severe than nearly any other vaccine. It doesn’t matter if the U.S. government has been using this vaccine for over a decade and has literally millions of health records to study. The critics will argue that the government hasn’t proven the vaccine’s efficacy for adults, let alone children. And they’d be right, technically; but it still works. This is a lousy argument.
The recommendation to test the vaccine for use on children is just wrong.>>>More
WASHINGTON (AP) — The Obama administration is asking a presidential commission to help decide an ethical quandary: Should the anthrax vaccine and other treatments being stockpiled in case of a bioterror attack be tested in children?
“We can’t just assume that what we have for adults works for children,”Health and Human Services Secretary Kathleen Sebelius told the panel Thursday.
Controversy over whether to open pediatric studies of the anthrax vaccine led Sebelius to ask the Presidential Commission for the Study of Bioethical Issues to tackle the question. The commission began its deliberations Thursday; recommendations are expected by year’s end.
Sebelius made clear that the question is far broader than anthrax.
 Short URL: http://www.newsnet14.com/?p=102940

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